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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESPN
All Species:
5.76
Human Site:
Y519
Identified Species:
21.11
UniProt:
B1AK53
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B1AK53
NP_113663.2
854
91733
Y519
K
Q
P
S
T
G
D
Y
Y
R
Q
L
G
R
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086470
1005
108024
Q518
E
K
Q
I
A
D
L
Q
L
R
R
R
C
Q
E
Dog
Lupus familis
XP_546751
854
91679
Y519
K
Q
P
S
T
G
D
Y
Y
R
Q
L
G
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET47
871
94479
L519
L
H
R
Q
D
S
G
L
L
R
Q
D
S
E
L
Rat
Rattus norvegicus
Q63618
837
90550
D518
N
T
G
L
R
R
Q
D
S
D
R
K
Q
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523384
1436
155315
S829
T
E
A
V
D
S
D
S
G
L
E
V
V
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791856
870
93835
A535
W
T
V
L
H
S
A
A
F
N
G
H
L
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
30.5
90.6
N.A.
76.3
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
20.2
Protein Similarity:
100
N.A.
43.8
93
N.A.
83
85.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
32.2
N.A.
N.A.
37.1
P-Site Identity:
100
N.A.
6.6
100
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
33.3
100
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
15
0
15
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
29
% C
% Asp:
0
0
0
0
29
15
43
15
0
15
0
15
0
15
0
% D
% Glu:
15
15
0
0
0
0
0
0
0
0
15
0
0
29
29
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
29
15
0
15
0
15
0
29
0
0
% G
% His:
0
15
0
0
15
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
29
15
0
0
0
0
0
0
0
0
0
15
0
0
0
% K
% Leu:
15
0
0
29
0
0
15
15
29
15
0
29
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
29
15
15
0
0
15
15
0
0
43
0
15
15
0
% Q
% Arg:
0
0
15
0
15
15
0
0
0
58
29
15
0
43
0
% R
% Ser:
0
0
0
29
0
43
0
15
15
0
0
0
15
0
15
% S
% Thr:
15
29
0
0
29
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
15
15
0
0
0
0
0
0
0
15
15
0
15
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
29
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _